Dendrimeric calcium-responsive MRI contrast agents with slow in vivo diffusion
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چکیده
منابع مشابه
Dendrimeric calcium-responsive MRI contrast agents with slow in vivo diffusion.
We report a methodology which enables the preparation of dendrimeric contrast agents sensitive to Ca(2+) when starting from the monomeric analogue. The Ca-triggered longitudinal relaxivity response of these agents is not compromised by undertaking synthetic transformations, despite structural changes. The in vivo MRI studies in the rat cerebral cortex indicate that diffusion properties of dendr...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2015
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c4cc07540d